Laboratory of Neurobiology

Faculty of Chemistry and Biology / Department of Biology

3 (1)

DESCRIPTION

The Laboratory of Neurobiology studies changes in the central nervous system and has developed new models of chronic pain compatible with the new standards of current bioethics. Research is always focused on the development of new therapies to alleviate patients with chronic pain.

Some of the contributions of the Laboratory include the novel description of the Pannexin-1 channel as critical for the perception of chronic pain; and the demonstration that the BDNF neurotransmitter is one of the factors that initiates neural changes that generate chronic pain. Regarding treatments, our research team has developed and patented various polymeric nanoparticles charged with bioactive molecules capable of inhibiting pain perception for several days with a single application.

SERVICES

Molecule effectiveness testing in different pathology models (pain, addiction, motor alterations)

Detection of antigens in biological tissues through immunehistochemical and immunofluorescence techniques

RESEARCH LINE

Chronic pain neurobiology

Development of polymeric nanoparticles with painkilling and agroindustrial applications

Development and synthesis of polymeric nanoparticles

EQUIPMENT

STAFF

Luis Constandil
Director of laboratory

Alejandro Hernández
Tenured professor

Jeffri Retamal
Associated researcher

Yaquelin González
Laboratory administrator

Nicolás Oneto
Research assistant

Natalia Juica
PhD in Biology candidate

María Triolo
PhD in Neuroscience candidate

CONTACT INFORMATION

Contact:
luis.constandil@usach.cl – laboratorio.neurobiología@gmail.com
Phone: +56227181092
Location: Outer wing of the Faculty of Chemistry and Biology

ADDRESS
Casa Central, Primer piso
Av. Libertador Bernardo O’Higgins 3363, Estación Central, Santiago de Chile.

TELEPHONE
(+56-2) 271 80047

E-MAIL
comunicaciones.vriic@usach.cl