The Laboratory conducts research on the physical properties of the biological activity of the systems under study. It focuses on cellular adaptation to external forces, the characterization of mechanical properties of the studied cells and, more recently, the identification of the biological activity through the detection of fluctuations in systems where thermal fluctuations predominate. To address these problems of physical and biological interest, our research team has built and developed ad-hoc experimental techniques such as optical tweezers and the detection of fluctuations through laser interferometry, complemented by Fourier analysis, correlations and wavelets for characterizing complex systems.